Hypolipidemic agent "Simgal": instructions for use
Pharmaceutical action of the drug
The drug "Simgal" instructions for use is defined as a lipid-lowering agent of synthetic origin. Prolonged use of this drug can reduce the content of low-density lipoprotein in plasma and increase the concentration of high-density lipoprotein. If we talk about the pharmacokinetics of this tool, then the highest plasma concentration of the active component is observed already after sixty-one hundred and twenty minutes after taking Simgal. Instructions for use in this case notes that the maximum therapeutic effect is fixed after one to two months of constant use of the drug.
Features of the composition of the drug
This lipid-lowering drug is produced in the form of tablets, which can contain ten, twenty or forty milligrams of simvastatin, which acts as an active substance.Additional ingredients are magnesium stearate, butyl hydroxyanisol, microcrystalline cellulose, ascorbic acid, lactose monohydrate, citric acid monohydrate, and pregelatinized starch.
The scope of the drug
To prescribe tablets "Simgal" instructions for use mainly advises for the treatment of patients suffering from primary hypercholesterolemia or mixed hyperlipidemia. In addition, this lipid-lowering drug can be used to prevent myocardial infarction in ischemic heart disease. To slow down the development of atherosclerosis also recommends prescribing this medication instruction. Simgal can also be used to reduce the risk of a revascularization procedure. And, finally, this drug is very effective in cerebrovascular disease.
Main contraindications for use
Appoint hypolipidemic agent "Simgal" instructions for use is not recommended for acute forms of various liver diseases, porphyria and individual sensitivity to simvastatin.During pregnancy, during breastfeeding, and in the case of elevated serum transaminase levels, plasma serum should also be avoided. In addition, the list of contraindications includes the children's age of the patient (up to eighteen years).
Possible adverse conditions
Prolonged use of this lipid-lowering drug can cause abdominal pain, vomiting, flatulence, nausea, diarrhea, pancreatitis, asthenic syndrome, dizziness and insomnia. Myalgia, myopathy, rhabdomyolysis, convulsions, visual impairment and peripheral neuropathy may also occur as a result of taking Simgal tablets.