Amylase pancreatic differs from amylaseintestines, salivary glands and other internal organs by its amino acid sequence and properties. It was these differences that served as an excuse for developing and using the most reliable method of diagnosing such a disease as acute pancreatitis. It is carried out by determining the pancreatic isoamylase, which is produced in the pancreas. In addition to identifying such a serious disease as pancreatitis, this analysis allows you to determine the presence in the body of a number of other serious diseases.
There are many indications for the administration of amylase analysis of pancreatic. These include:
- cystic fibrosis;
- pathology of the pancreas;
- Abdominal sharp pains.
The enzyme amylase pancreatic is greatly increasedat occurrence of an acute pancreatitis (in tens times above norm or rate, thus that the maximum activity is shown in the initial 12 hours of the disease); epidemic parotitis (pancreatic disease); blockage of ducts of the gland (stones, tumors, adhesions); exacerbation of chronic pancreatitis; postoperative conditions, pancreatic cyst; endoscopic retrograde cholangiopancreatography, abdominal injuries, peritonitis, chronic alcoholism.
Amylase is lowered in case of pancreatic insufficiency, severe cystic fibrosis and severe liver damage.
Detection of pancreatic amylase in the urinethe patient indicates severe damage to the pancreas. Data on the content of amylase in the assays allow the diagnosis of the disease in a timely manner and the patient to be given the necessary treatment. After the course of treatment, repeated laboratory tests are performed to determine the result of the therapy.
Pancreatic amylase is determined by both urine analysis and by detecting its concentration in the patient's blood.
Before conducting a urine test, strictrestrictions in the patient's diet are almost not required. For an effective study, you need to provide an average portion of urine (one-time). Its volume should be not less than 20 ml. The temperature of the urine when transferred to the laboratory should not be above 8 ° C. At the time of the analysis, it is necessary to find out whether the patient is taking any medications that affect the results of the analysis. The best result can be obtained only if the patient completely refuses to take any medications. During this period, you can not use any alcoholic beverages. There are a number of substances that affect the results of the analyzes. They include all medicines, alcohol, oxalates, citrates, fluorides, EDTA.
Amylase pancreatic is characterized bya certain activity, for which several units of measure are used. Depending on the methods of laboratory tests, the normal parameters may vary. For each specific case, a certain type of analysis of pancreatic amylase is required.
The blood test for the content of amylase is carried out8-12 hours after eating. Violation of this rule can completely distort the results of research. During the test, the use of juices, tea and coffee is unacceptable. At this time you can drink only ordinary water. Modern methods of analysis allow you to get an accurate result in just 1 day. There is an even faster express method, in which data can be obtained after 3 hours.
Accuracy of the results ofall the requirements of laboratory research is not questioned. It is through the development of such diagnostic methods that a large number of people are safely cured of serious diseases, somehow related to the functioning of the pancreas.